Description

Who We Are

BioMarin is a leading rare disease biotechnology company focused on genetically defined conditions.

Guided by our purpose to develop medicines that make a profound impact on people’s lives, our global teams have delivered a portfolio of therapies since our founding in 1997. Our revolutionary treatments for conditions like achondroplasia (the most common form of dwarfism), PKU (phenylketonuria), CLN2, a form of Batten disease, and a number of forms of MPS (mucopolysaccharidosis) offer new possibilities for patients and families who previously had few, if any, available options. More recently, with the close of the Amicus acquisition, our portfolio has expanded to include therapies for Fabry disease and Pompe disease, expanding our ability to reach more people living with rare genetic conditions.

Our success comes from our unwavering commitment to excellence, our deep understanding of patient needs, our scientific expertise, and our world-class manufacturing capabilities. At the heart of BioMarin is a dedicated team of the brightest minds in the industry working together to deliver innovative therapies to patients and families around the world.

About Technical Operations

BioMarin’s Technical Operations group is responsible for creating our drugs for use in clinical trials and for scaling production of those drugs for the commercial market. These engineers, technicians, scientists and support staff build and maintain BioMarin’s cutting-edge manufacturing processes and sites, provide quality assurance and quality control to ensure we meet regulatory standards, and procure the needed goods and services to support manufacturing and coordinating the worldwide movement of our drugs to patients.

About TOPS Digital, Data and Operational Excellence  

TOPS Digital, Data & Operational Excellence exists to find the opportunities that matter most and turn them into measurable, sustained business value. The function brings together three connected pillars: Data Science, Analytics & AI; Operational Excellence; and Digital Strategy & Value Delivery. Together, these capabilities help identify opportunities, improve how work gets done, and deliver greater impact across TOPS. The function focuses on opportunities across sites, functions, and value streams where a coordinated approach can deliver greater value. Through one TOPS-wide portfolio of priorities, ranked by business value, the team works in partnership with functions, sites, and DTA to take opportunities from insight through improvement to impact.  

Data Science, Analytics & AI uses trusted data and insights to identify where value exists; Operational Excellence simplifies and improves processes using proven methodologies; and Digital Strategy & Value Delivery prioritizes opportunities, uses digital solutions to scale, and sustain improvements. Working in partnership with the business, the function helps define and enable the value of opportunity, while business teams remain accountable for delivering and sustaining results.  

Role Summary 

Reporting to the Head, Digital Strategy & Value Delivery, the Director/  Senior Director, Value Delivery Lead leads finite, cross-functional value pursuits across TOPS sites, functions, value streams and the external network. The role focuses on opportunities that improve gross margin, inventory to cash and end-to-end speed while protecting patient supply, quality, and safety.

Working with named business owners, Data Science, Analytics & AI, Operational Excellence, Digital Strategy & Value Delivery, DTA, Quality and Finance, the Value Lead converts prioritized opportunities into measurable, sustained business value. The role owns the integrated pursuit plan, coordinates delivery through Frame, Baseline, Simplify, Digitize and Prove, and brings the evidence required at each decision gate.

The role leads through matrix relationships and charter-based authority, aligning named contributors around agreed outcomes, capacity, targets, and timing. The Value Lead is accountable for pursuit delivery and value evidence. Site and functional leaders retain accountability for operating decisions, people, budgets, adoption and sustained operating outcomes; DTA retains technical, build and run authority; Quality retains regulated controls; and Finance retains authority for financial benefit validation, recognition and attribution.

Key Responsibilities: 

• Shape and charter pursuits: Identify opportunities aligned to TOPS strategy and the LRP; agree the business owner, outcome, scope, targets, measures, resources, dependencies, timing and decision rights.  
• Build the value case: Establish a trusted baseline, validate root causes and quantify benefits, costs, assumptions and risks with business owners, Data Science, Operational Excellence and Finance. Distinguish benefit types and prevent double counting, using methods agreed with Finance.  
• Lead integrated delivery: Own the pursuit plan and coordinate work across business teams, the three DDOE pillars, DTA, Quality and Finance through Frame, Baseline, Simplify, Digitize and Prove.
• Simplify before digitizing: Partner with Operational Excellence and business owners to address root causes, improve and control the process, and build operating capability before applying technology where it adds value.
• Secure commitments and resolve trade-offs: Confirm named resources and capacity; surface changes in value, scope, timing or dependencies; and bring options through the Head, Digital Strategy & Value Delivery, escalating unresolved TOPS priority decisions to the VP DDOE.
• Maintain governance and controls: Preserve business-owner accountability, DTA technical authority, Quality approvals and Finance authority for benefit validation, recognition and attribution. Provide cases and outcome evidence to the Portfolio & Benefits Lead for portfolio review and consolidated reporting.
• Drive adoption and handover: Coordinate readiness, training and handover with business owners, ensuring standard work, controls, measures and support are in place and securing formal business acceptance.
• Prove, close and scale: Evidence results and report shortfalls transparently. Close when Finance has validated applicable benefits, the business owner has accepted handover, agreed results are sustained, and a monitoring owner and plan are in place. Obtain approval for extensions and capture learning for replication.

KPIs & Metrics: This role will influence:

• Gross margin, cost of goods and Finance-validated financial benefits, net of implementation and sustainment costs.  
• Inventory to cash, including DIOH, working capital, lead time, expiry, waste and supply reliability, as relevant to the pursuit.
• End-to-end speed, including development, technical transfer, release, planning or operational cycle time, as relevant to the pursuit.
• Patient supply, quality, safety, right-first-time performance, capacity and service outcomes, without displacing line accountability.
• Pursuit quality and execution: baseline confidence, gate readiness, delivery against chartered scope and timing, adoption, sustained performance, transparent risk reporting and completeness of benefit evidence.
• Charter targets, benefit measures, sustainment periods and monitoring intervals are agreed with business owners and Finance. The Value Lead is accountable for the integrated pursuit plan, delivery coordination and outcome evidence; business owners remain accountable for operating results and adoption, and Finance retains authority for financial validation, recognition, attribution and recurring target credit.

Qualifications

Required

• Bachelor’s degree in engineering, science, supply chain, business or a related discipline.  
• Senior pharmaceutical or biotechnology operational experience across manufacturing, quality, supply chain, technical development or engineering, with credibility to work across site, functional and network leadership.
• Demonstrated delivery of complex, cross-functional improvements with quantified value, named owners, committed resources, effective adoption and sustained outcomes after handover.
• Strong financial and business-case fluency, including baselines, sensitivities, full costs, benefit methods and attribution, together with the ability to manage competing objectives and dependencies through matrix leadership.
• Working knowledge of GMP, change control, validation and data integrity, with judgement to engage Quality and DTA early and translate operational needs into clear requirements, controls and acceptance criteria.
• Requires a min of 10 years of experience in pharmaceutical, biotechnology, regulated manufacturing, supply chain, or MS&T environments. With a minimum of 7 years of experience leading operational excellence, transformation, business process, performance analytics, or strategic improvement projects

Preferred

• Lean Six Sigma Black Belt or an equivalent demonstrated record of personally delivered, sustained improvement.  
• Experience designing or improving end-to-end processes across sites, functions or external partners, such as plan-to-produce, technical transfer, inventory, capacity, deviation or release flows.
• Experience delivering digitally enabled operational change through analytics, AI, process mining, automation or enterprise/manufacturing systems in partnership with accountable technology and Quality teams.
• Experience across sites or functions in more than one country. An advanced degree in a relevant discipline is an advantage.

Core Competencies

• Evidence-led collaborative influence: constructs clear cases, translates complex trade-offs into clear choices for senior leaders, challenges assumptions respectfully, negotiates cross-functional commitments and maintains trust through difficult decisions.
• Analytical and financial judgement: explains uncertainty, tests benefit logic, distinguishes local improvement from total-system value and reports shortfalls honestly.
• Patient-centered systems thinking and change leadership protects quality, safety and reliable supply while building capability, adoption and ownership that survive the pursuit team’s release.

Travel Requirements

Travel to manufacturing sites, functional locations and relevant external partners, including internationally, for discovery, pursuit of delivery, business acceptance and sustainment reviews. Travel follows the scope and needs of assigned pursuits rather than a permanent site assignment.

Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned.

Equal Opportunity Employer/Veterans/Disabled

An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

Ireland Safety Responsibility Support the organisation’s commitment to environmental protection, injury prevention, and continual improvement of EHS management systems. Actively contribute to a safe and environmentally responsible workplace by identifying hazards, reporting incidents and participating in EHS initiatives and training.
Ireland Safety Responsibility

Support the organisation’s commitment to environmental protection, injury prevention, and continual improvement of EHS management systems. Actively contribute to a safe and environmentally responsible workplace by identifying hazards, reporting incidents and participating in EHS initiatives and training.